Exemestane

Exemestane

Product Category: Pharmaceutical raw materials and intermediates

Product content: ≥ 99%

CAS:107868-30-4

Molecular formula: C20H24O2

Molecular Weight:296.40

Molecular Structure:
 

Packing specifications: 25kg / barrel
Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal women. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation.
Appearance: White or Almost White Crystalline Powder
Indication:For the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy

Pharmacodynamics
Aromatase is an enzyme that converts hormones to estrogen in the body's adrenal glands. The aromatase inhibitors (AIs) are drugs that reduce estrogen levels by blocking the action of aromatase in the adrenal glands. The selective AIs (SAIs) selectively reduce levels of estrogen without interfering with levels of other steroid hormones that are produced by the adrenal gland. Drugs in this class include anastrozole (Arimidex ™), letrozole (Femara ™) and exemestane (Aromasin ™).
MORE INFORMATION PLS CONTACT
[email protected]
tel:86-027-50756155
shype:[email protected]